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TIGIT inhibitor drugs
TIGIT (T cell immunoglobulin and ITIM domain), also known as VSig9, Vstm3, or WUCAM, is an inhibitory receptor member of the CD28 family. TIGIT binds to CD155 (PVR or Necl-5) with high affinity and weakly interacts with CD112 (PVRL2, nectin-2). TIGIT also competes with other counterparts, CD266 (DNAM-1) or CD96, to exert its immunosuppressive effects. Learn more:
TIGIT inhibitor drugs
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